Publications by authors named "Emilia Pawlowski"
Article Synopsis
- Seatbelt use significantly reduces the risk of injury and death in vehicle crashes, but rear-seated adults are less likely to wear them compared to those in the front seat.
- A study analyzed data from nearly 1 million adults involved in crashes in New York, finding that rear-seated occupants had a 1.5 times higher mortality rate and were more often unrestrained.
- Factors like speeding, a drinking driver, and older vehicles were linked to higher injury severity, highlighting that unrestrained rear-seated occupants face greater risks than their restrained front-seated counterparts.
Unlabelled: There are reports that historically higher mortality observed for front- compared to rear-seated adult motor vehicle (MV) occupants has narrowed. Vast improvements have been made in strengthening laws and restraint use in front-, but not rear-seated occupants suggesting there may be value in expanding the science on rear-seat safety.
Methods: A linked 2016-2017 hospital and MV crash data set, the Crash Outcomes Data Evaluation System (CODES), was used to compare characteristics of front-seated ( = 115,939) and rear-seated ( = 5729) adults aged 18 years and older involved in a MV crash in New York State (NYS).
Background: In New York State (NYS), motor vehicle (MV) injury to child passengers is a leading cause of hospitalization and emergency department (ED) visits in children aged 0-12 years. NYS laws require appropriate child restraints for ages 0-7 years and safety belts for ages 8 and up while traveling in a private passenger vehicle, but do not specify a seating position.
Methods: Factors associated with injury in front-seated (n = 11,212) compared to rear-seated (n = 93,092) passengers aged 0-12 years were examined by age groups 0-3, 4-7 and 8-12 years using the 2012-2014 NYS Crash Outcome Data Evaluation System (CODES).
Objective: To assess variation in genes that regulate cholesterol metabolism in relation to the natural history of HIV infection.
Design: Cross-sectional and longitudinal analysis of the Women's Interagency HIV Study.
Methods: We examined 2050 single nucleotide polymorphisms (SNPs) in 19 genes known to regulate cholesterol metabolism in relation to HIV viral load and CD4 T-cell levels in a multiracial cohort of 1066 antiretroviral therapy-naive women.
A series of 4-arylimidazole carbamates was synthesized and their binding affinities to the site-2 sodium (Na+) channel were determined. SAR studies led to the identification of compound 10, a potent Na+ channel blocker which was efficacious in pain models in vivo.
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