Publications by authors named "Emil Wanngren"
Article Synopsis
- A stereocontrolled total synthesis of (-)-stemoamide starts from (S)-pyroglutaminol and involves several key intermediate steps.
- The synthesis utilizes chemoselective iodoboration and a Pd(0)-catalyzed Negishi cross-coupling to create significant intermediates, followed by a ring-closing metathesis reaction.
- The final product's specific C8-C9 trans-stereochemistry is achieved through a stereoselective bromolactonization process followed by 1,4-reduction.
