Publications by authors named "Emil Tonon"

The availability of new technologies for deep sequencing, including next-generation sequencing (NGS), allows for the detection of viral genome variations. The epidemiological determination of SARS-CoV-2 viral genome changes during the pandemic waves displayed the genome evolution and subsequent onset of variants over time. These variants were often associated with a different impact on viral transmission and disease severity.

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Flaviviruses cause numerous pathologies in humans across a broad clinical spectrum with potentially severe clinical manifestations, including hemorrhagic and neurological disorders. Among human flaviviruses, some viral proteins show high conservation and are good candidates as targets for drug design. From an epidemiological point of view, flaviviruses cause more than 400 million cases of infection worldwide each year.

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Article Synopsis
  • * The deletion preserved part of ORF7b and ORF8 while likely forming a hairpin structure due to small repeats flanking the deleted region.
  • * Similar deletions were found in 15 sequences in the NCBI database, with a notable link to immunodeficient patients, suggesting that such conditions may facilitate the emergence of these mutations.
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Ethylene is a plant hormone widely used to ripen fruit. However, the synthesis, handling, and storage of ethylene are environmentally harmful and dangerous. We engineered E.

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