Volumetric changes in brain MRI of infants with hypoxic-ischemic encephalopathy and abnormal neurodevelopment who underwent therapeutic hypothermia.

Background: Hypoxic-ischemic encephalopathy (HIE) is a severe neonatal complication that can result in 40-60 % of long-term morbidity. Magnetic Resonance Imaging (MRI) is a noninvasive method which is usually performed before discharge to visually assess acquired cerebral lesions associated with HIE and severity of lesions possibly providing a guide for detecting adverse outcomes. This study aims to evaluate the impact of HIE on brain volume changes observed in MRI scans performed at a mean 10 days of life, which can serve as a prognostic indicator for abnormal neurodevelopmental (ND) outcomes at 18-24 months among HIE infants.

Change of coagulation after NovoSeven® use for bleeding during cardiac surgery.

Objectives Recombinant activated factor VII has been used for the treatment of hemophilia, factor VII deficiency, and Glanzmann's thrombasthenia. Off-label uses have recently been increasing, and there are reports that recombinant activated factor VII is effective for the treatment of excessive bleeding during or after cardiovascular surgery. We retrospectively reviewed the effectiveness of recombinant activated factor VII and its influence on the coagulation system as a treatment for uncontrollable bleeding during cardiovascular surgery.

[Efficacy of Recombinant Activated Factor VII for Intractable Bleeding after Cardiovascular Surgery].

Unlabelled: Recombinant activated factor VII (rFVIIa) has been used for the treatment of hemophilia, factor VII deficiency, and Glanzmann's thrombasthenia. We retrospectively reviewed the effectiveness of rFVIIa for the treatment of uncontrollable bleeding after cardiovascular surgery.

Material And Methods: Eight patients received rFVIIa for the treatment of uncontrollable bleeding after admission to the intensive care unit following cardiovascular surgery between April 2009 and July 2014.

[Invalid sensors judged by the BIS A-2000 monitors may display clinically acceptable BIS values on the external equipments].

The bispectral index (BIS) is widely used to measure anesthetic levels in the perioperative period. In our hospital, the BIS monitors (A-2000) are connected to bedside monitors and display BIS values on them through outside input. All datas on the bedside monitors are transmitted to anesthesia information management system automatically.

Self-assembly of active IrO2 colloid catalyst on an ITO electrode for efficient electrochemical water oxidation.

Active catalysts for water oxidation to evolve O(2) are required for the construction of artificial photosynthetic devices that are expected to be promising energy-providing systems in the future. The citrate-stabilized IrO(2) colloid was self-assembled onto an indium tin oxide (ITO) electrode to form a monolayer of the colloidal IrO(2) particles when it was dipped in the colloid solution. The self-assembly could be achieved by a chemical interaction between carboxylate groups on the citrate stabilizer and hydroxyl groups on the ITO surface to form ester bonds.