Publications by authors named "Emi Sakurai"

Atopic dermatitis (AD) places a burden on work productivity. Recently, dupilumab was approved for AD, but its impact on work productivity in Japanese patients has not been reported. Furthermore, data on the effect of long-term treatment with dupilumab on work productivity are limited.

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Article Synopsis
  • Psoriasis is linked to abnormal blood vessel development, and this study aimed to analyze serum levels of angiogenesis-related factors in psoriasis patients compared to healthy controls.
  • The research involved 10 healthy subjects and 55 psoriasis patients, measuring factors like angiopoietin-1, VEGF, and EGF, revealing that psoriasis patients exhibited altered levels of these factors compared to controls.
  • Results indicated that certain angiogenesis-related factors, such as VEGF and FGF-basic, correlated with the severity of psoriasis, suggesting potential implications for understanding the disease and its treatment response.
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Hypertension is one of the most important cardiovascular risk factors and results in macrophage infiltration of blood vessels. However, how macrophages coordinate inflammatory responses with endothelial cells (ECs) remains unclear. In this study, we investigated whether exosomes upregulate the expression of inflammatory factors in ECs under hypertensive conditions.

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