Blueberry juice augments exercise-induced neuroprotection in a Parkinson's disease model through modulation of GDNF levels.

Exercise and consumption of plant-based foods rich in polyphenols are attractive therapeutic approaches for the prevention and treatment of Parkinson's disease (PD). Few studies, however, have examined the neuroprotective efficacy of combining these treatment modalities against PD. Therefore we investigated whether combining voluntary running and consumption of blueberry juice (BBJ) was more efficacious against 6-hydroxydopamine (6-OHDA) toxicity than either treatment alone.

Are Guidelines Important? Results of a Prospective Quality Improvement Lumbar Fusion Project.

Background: United States (U.S.) healthcare is a volume-based inefficient delivery system.

Using a tree diagram to interpret a mixed DNA profile.

A recent case is described where the evidence of bloodstaining on a knife suggested that it was a mixture from the two victims. Interpretation of the evidence in this problem necessitated the formulation of several sets of multiple hypotheses which were analyzed by means of a tree diagram. The problem was then greatly simplified to one of comparing the two alternative hypotheses of most interest.

The relationship between follicle diameter, fertilization rate, and microscopic embryo quality.

The diameter of preovulatory ovarian follicles was measured at the time of transvaginal US-guided oocyte retrieval, and the oocytes were subsequently examined to assess fertilization rates and the quality of developing embryos. With follicles divided into three groups of increasing diameter, there were no significant differences in the fertilization rates of oocytes recovered from follicles of different size. Embryo quality improved with increasing follicle size, although the differences were not highly significant.

The effect of carcinoma of the cervix on the L-lactate-nicotinamide-adenine dinucleotide oxidoreductase activity in vaginal aspirates.

Lactate dehydrogenase (L-lactate-NAD+ oxidoreductase; EC 1.1.1.

The effect of the menopause on the L-lactate-nicotinamide-adenine dinucleotide oxidoreductase activity in vaginal aspirates.

Lactate dehydrogenase (L-lactate-NAD+ oxidoreductase; EC 1.1.1.

The detection of Y chromosomes in bloodstains--a reevaluation.

A method has been described for detecting Y chromosomes in the leukocytes of human bloodstains prepared on a variety of substrates. The factors that influence the proportion of chromosomes exhibiting a Y spot (the Y cell index) in a bloodstain are considered, including the subjective nature of assessment of the Y chromosome fluorescence, the substrate, and the age of bloodstain. In contrast to previous workers no decay in Y cell index with the age of the stain was observed.

The separation of plasma lipoproteins using gel electrofocusing and polyacrylamide gradient gel electrophoresis.

Polyacrylamide gel electrofocusing and gradient electrophoresis have been used to separate the lipoproteins in whole plasma and in fractions prepared by sequential flotation in the ultracentrifuge and by precipitation with dextran sulphate and manganous chloride. After the two-dimensional separation, high density lipoproteins appear as a zone showing noticeable heterogeneity with respect to both isoelectric point and molecular weight. Low density lipoproteins are resolved as a compact spot while very low density lipoproteins are visible as a long horizontal streak across the top of the electrophoresis gel.

Studies on the binding of haemoglobin by haptoglobin using electrofocusing and gradient electrophoresis.

1. Gel electrofocusing followed by gel gradient electrophoresis separated the haptoglobins and their complexes with haemoglobin into characteristic two-dimensional patterns of protein bands. 2.

Electrofocusing followed by gradient electrophoresis: a two-dimensional polyacrylamide gel technique for the separation of proteins and its application to the immunoglobulins.

A two-dimensional polyacrylamide gel technique for the separation of proteins is described. Electrofocusing in a 3.5% polyacrylamide gel is followed by electrophoresis through a 4-24% concave polyacrylamide gel gradient.

The preparation of crystalline human L-lactate--nicotinamide--adenine dinucleotide oxidoreductase isoenzyme 1 involvoing preparative polyacrylamide-gel electrophoresis.

A method is presented for the preparation of human heart lactate dehydrogenase (l-lactate-NAD(+) oxidoreductase; EC 1.1.1.

The degradation of L-histidine in the rat. The formation of imidazolylpyruvate, imidazolyl-lactate and imidazolylpropionate.

1. Soluble and mitochondrial forms of histidine-pyruvate aminotransferase were separated from rat liver preparations by chromatography on DEAE-cellulose. 2.