Factors associated with 5-min APGAR score, death and survival in neonatal intensive care: a case-control study.

Background: The 5-minute APGAR score is clinically used as a screening tool to assess how the newborn has reacted to previous care, remaining relevant for predicting neonatal survival. This study aimed to analyze the determinants of the 5th minute APGAR score, and the factors associated with the death and survival of newborns with low APGAR scores hospitalized in the neonatal intensive care unit (NICU) at a referral public hospital in North Brazil.

Methods: This was a hospital-based retrospective case-control study with 277 medical records.

Effects of adjuvant-induced arthritis on the ventral prostate of rats treated with angiotensin AT receptor blocker.

Aims: To analyze the prostatic compartments, extracellular matrix, microvascularization, transforming growth factor-beta (TGF-β) and angiotensin II receptors type 1 (AT) levels, and histopathology of the ventral prostate in a rat model for rheumatoid arthritis, and to evaluate the effect of angiotensin II AT receptor blocker (ARB) in the disease.

Main Methods: Fifteen male rats (90 days old) were divided into three groups (n = 5/group): control, adjuvant-induced arthritis without (AIA) or with AT receptor blocker (AIA + ARB). Animals were euthanized 60 days after immunization.