[Detection of ALK and ROS1 rearrangements by immunocytochemistry on cytological samples].

The identification of ALK and ROS1 rearrangements has become essential for the theranostic management of patients with non-small cell lung cancer, especially in stage IV or inoperable patients. These testings are now performed by immunohistochemistry on histological samples and confirmed by fluorescent in situ hybridization in case of positive or doubtful results. The diagnosis of lung cancer is often performed at an advanced or metastatic stage and cytological sample could be the only material containing malignant cells available at these stages.

Knowledge, attitude and behavior of mothers related to acute respiratory infections.

Background: The aim of this paper was to evaluate the level of knowledge and general attitude to acute respiratory diseases and behavior of antibiotic usage and related factors.

Methods: The study included 122 mothers of children between 2 and 16 years of age who applied the complaint of respiratory infections and experienced the respiratory infections previous year, to policlinics between January and May 2012. A survey form was used to evaluate the sociodemographic properties of the mothers, and the level of knowledge, attitude and behavior of mothers to childhood acute respiratory infections, fever and antibiotic use.