Publications by authors named "Emeka Chukwuka"
Article Synopsis
- Hepatocellular carcinoma (HCC) is a type of liver cancer that is difficult to treat and resistant to chemotherapy, prompting research into alternative therapies.
- The study focused on evaluating the compounds from the Noni tree to find potential inhibitors of B-Raf kinase, a target in HCC treatment, using various computational techniques.
- Five compounds, including Soranjidiol, showed promising inhibitory activity against B-Raf kinase and demonstrated good drug-like properties, suggesting they could be developed into new treatments for HCC.
Objectives: There are several clinical practice guidelines available for peripheral artery disease (PAD). The paucity of strong evidence is known to give room for variations in recommendations across guidelines, with attendant confusion among clinicians in clinical practice. This study aims to conduct a quality assessment and comparative analysis on PAD screening and diagnostic recommendations in PAD management.
View Article and Find Full Text PDFIntroduction: Peripheral arterial disease (PAD) is the third leading atherosclerotic arterial disease. There is evidence that there is a high variation in the quality and recommendations of clinical practice guidelines for PAD, leading to the possibility of confusion among clinicians and patients. This study aims to conduct a quality assessment and comparative analysis of the clinical practice guidelines on PAD written between 2010 and 2020.
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