Publications by authors named "Emanuelle Marques"
The Influence of Initial Immunosuppression on the Kinetics of Humoral Response after SARS-CoV-2 Vaccination in Patients Undergoing Kidney Transplantation.
Vaccines (Basel)
October 2024
The effect of initial immunosuppressive therapy on the kinetics of the SARS-CoV-2 vaccine-induced humoral response is unknown. Here, we compared the kinetics of SARS-CoV-2 vaccine-induced humoral response in chronic kidney disease patients undergoing kidney transplantation (KTRs) and compared to patients remaining on dialysis during the Omicron circulation. This prospective, non-randomized, real-world study included 113 KTRs and 108 patients on dialysis.
View Article and Find Full Text PDFGenome-wide association study for Chagas Cardiomyopathy identify a new risk locus on chromosome 18 associated with an immune-related protein and transcriptional signature.
PLoS Negl Trop Dis
October 2022
Article Synopsis
- - Chronic Chagas Cardiomyopathy (CCC) develops years after parasitic infection and is a major cause of heart failure in Latin America, yet only a small percentage of infected individuals develop the disease.
- - A genome-wide association study (GWAS) identified a new susceptibility locus (rs34238187) linked to CCC in Brazilian populations, with significant associations to various immune-related traits.
- - The findings suggest that this genetic locus plays a role in modifying the immune response to the T. cruzi parasite, highlighting the need for further research into its functional character and impact on CCC risk.
The coronavirus disease 2019 (COVID-19) pandemic has changed the paradigms for disease surveillance and rapid deployment of scientific-based evidence for understanding disease biology, susceptibility and treatment. We have organized a large-scale genome-wide association study (GWAS) in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infected individuals in Sao Paulo, Brazil, one of the most affected areas of the pandemic in the country, itself one of the most affected in the world. Here, we present the results of the initial analysis in the first 5233 participants of the BRACOVID study.
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