Publications by authors named "Emanuela Oana Costin"

Sarcoidosis is a complex inflammatory disease of uncertain origin, characterized by non-necrotizing epithelioid cell granulomas (NNEGs) affecting multiple organ systems. Although many different clinical and pathological phenotypes can be present, with different organs involved, the lung is the most common site described. In this case report, we (a) present and discuss the broad differential diagnosis of a patient presenting with a solitary lung mass with clinical and imaging features of lung cancer that ultimately was confirmed with a rare manifestation of stage II pulmonary sarcoidosis, and (b) analyze and compare similar cases from the literature.

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For COVID-19 pneumonia, many manifestations such as fever, dyspnea, dry cough, anosmia and tiredness have been described, but differences have been observed from person to person according to age, pulmonary function, damage and severity. In clinical practice, it has been found that patients with severe forms of infection with COVID-19 develop serious complications, including pneumomediastinum. Although two years have passed since the beginning of the pandemic with the SARS-CoV-2 virus and progress has been made in understanding the pathophysiological mechanisms underlying the COVID-19 infection, there are also unknown factors that contribute to the evolution of the disease and can lead to the emergence some complications.

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Article Synopsis
  • SARS-CoV-2 can cause significant muscular damage by triggering inflammation, a cytokine storm, muscle breakdown, and complications like myopathy and polyneuropathy, impacting muscle function.
  • Research reviewed included 33 articles focused on muscle health after SARS-CoV-2 infection, utilizing various databases and recent studies from the past five years to gather relevant data.
  • Pulmonary rehabilitation and early mobilization are key in improving recovery, helping patients decrease breathlessness, enhance physical ability, and boost overall quality of life post-infection.
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