Publications by authors named "Emanuela Folco"

Background: Web discussions on health issues are becoming very relevant in the general public. In this context, little information is available regarding cardiovascular diseases, which remain the first cause of morbidity, disability and mortality worldwide. The central objective of the study was to conduct a Web listening analysis on discussions about cardiovascular diseases in Italy, comparing the data relative to the 2-year pre-COVID-19 pandemic period with those collected during the COVID-19 pandemic lockdown (March-July 2020), with quantification of conversations on cardiovascular disease and Web-based discussions and specific evaluation of COVID-19 lockdown impact.

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Article Synopsis
  • - The guidance focuses on improving care for familial hypercholesterolaemia (FH), a genetic condition that can lead to early heart disease and affects around 35 million people globally, many of whom are undiagnosed or not receiving proper treatment.
  • - It compiles effective clinical strategies for detecting and managing FH, addressing both lifelong care practices and implementation strategies across different healthcare systems.
  • - The goal is to integrate evidence-based recommendations with expert consensus to enhance patient outcomes and ensure comprehensive FH management worldwide.
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Background: Implementing evidence-based management of dyslipidaemia is a challenge worldwide.

Objectives: To understand physician beliefs and behaviour and identify uncertainties in dyslipidaemia management across four world regions.

Methods: Web-based survey of 1758 physicians in Japan, Germany, Colombia and the Philippines who were selected randomly from existing databases.

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Article Synopsis
  • - Familial hypercholesterolemia (FH) is a genetic condition affecting 1 in 200 to 250 people globally, causing severe health risks due to lack of diagnosis and treatment, with only 10% of cases being identified.
  • - The World Health Organization designated FH as a public health priority in 1998 and issued 11 recommendations to improve its diagnosis, treatment, and awareness, but there has been minimal progress in their implementation over the last two decades.
  • - In 2018, the FH Foundation and World Heart Federation held meetings to update these recommendations by gathering input from international stakeholders across various income regions to address gaps and enhance FH management.
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A large body of evidence supports the notion that incorrect or insufficient nutrition contributes to disease development. A pivotal goal is thus to understand what exactly is appropriate and what is inappropriate in food ingestion and the consequent nutritional status and health. The effective application of these concepts requires the translation of scientific information into practical approaches that have a tangible and measurable impact at both individual and population levels.

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The benefits achieved by implementing cardiovascular prevention strategies in terms of reduced incidence of atherosclerotic diseases and mortality are accepted, worldwide. In particular, the clinical management of hypercholesterolemia has a fundamental role for all preventive strategies, both in primary and secondary prevention, at each stage of cardiovascular risk. Since the net clinical benefit of lipid-lowering therapy largely depends on baseline individual cardiovascular risk profile, the assessment of individual risk is essential to establish type and intensity of both preventive and therapeutic strategies.

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Familial hypercholesterolaemia is common in individuals who had a myocardial infarction at a young age. As many as one in 200 people could have heterozygous familial hypercholesterolaemia, and up to one in 300 000 individuals could be homozygous. The phenotypes of heterozygous and homozygous familial hypercholesterolaemia overlap considerably; the response to treatment is also heterogeneous.

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