Publications by authors named "Emanuela Brambilla"

Vaginal health is an essential component of active and healthy aging in women at midlife and beyond. As a consequence of hormonal deprivation and senescence, the anatomy and function of urogenital tissues are significantly affected and vulvovaginal atrophy (VVA) may occur. In a high proportion of postmenopausal women, progressive and chronic VVA symptoms have a strong impact on sexual function and quality of life.

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Background: Protocols of controlled ovarian hyper-stimulation (COH) require, as a crucial step, the identification of reliable predictors of ovarian reserve. Anti-Mullerian hormone (AMH) is one of the most reliable predictors of ovarian reserve but other factors including autoimmune thyroid diseases (ATD) have been associated with reduced fertility and poor COH outcome. Aim of the present study was to evaluate the relationship between ATD and AMH, and their role on the outcome of COH.

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Article Synopsis
  • Controlled ovarian hyperstimulation (COH) is essential for assisted reproductive technology (ART), and autoimmune thyroid disease (ATD) can negatively impact COH outcomes; this study analyzed the effects of ATD and thyroid function on COH results in subfertile women.
  • The study involved 262 euthyroid women, comparing those with and without ATD, assessing key hormones and the performance of recombinant FSH (r-FSH) during the ART process.
  • Results showed that ATD-positive women had poorer r-FSH performance, but maintaining serum TSH levels below 2.5 mIU/L could improve outcomes, emphasizing the importance of checking thyroid function in women seeking ART.
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Among primary headaches, migraine is the form more sensitive to the ovarian hormonal milieu. Migraine without aura (MO) benefits from the hyperestrogenic state of pregnancy and the lack of hormonal fluctuations, while migraine with aura (MA) presents distinctive features. Indeed, a very strong improvement of MO has been documented across gestation, and only a minority of pregnant women still suffers during the third trimester.

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