Influence of Dopamine on Fluorescent Advanced Glycation End Products Formation Using .

Non-enzymatic glycation and covalent modification of proteins leads to Advanced Glycation End products (AGEs). AGEs are biomarkers of aging and neurodegenerative disease, and can be induced by impaired neuronal signaling. The objective of this study was to investigate if manipulation of dopamine (DA) in vitro using the model protein, bovine serum albumin (BSA), and in vivo using the model organism influences fluorescent AGEs (fAGEs) formation as an indicator of dopamine-induced oxidation events.