Publications by authors named "Emanuel F Bruno"
Background And Purpose: Status epilepticus (SE) is a neurological emergency due to prolonged seizure activity or multiple seizures without full recovery in between them. Prehospital SE management is crucial since its duration is correlated with higher morbidity and mortality rates. We examined the impact of different therapeutic strategies in the prehospital setting with a focus on levetiracetam.
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- The study aimed to investigate the treatment practices and effectiveness of benzodiazepines (BZDs) for patients experiencing status epilepticus (SE) in Cologne over two years.
- Out of 328 SE patients, only 72% were treated with BZDs initially, and just 21.6% received adequate doses as per guidelines; older patients and those with non-generalised seizures were less likely to be treated.
- The findings suggest that proper BZD dosing can significantly improve outcomes in generalised convulsive SE, while aggressive treatment in non-generalised forms may worsen results, highlighting the need for more research on treatment for these cases.
Background: The "coronavirus disease 2019" (COVID-19) pandemic, caused by the "severe-acute-respiratory-syndrome-coronavirus 2" (SARS-CoV-2), challenges healthcare systems worldwide and impacts not only COVID-19 patients but also other emergencies. To date, data are scarce on the extent to which the COVID-19 pandemic impacted status epilepticus (SE) and its treatment.
Objective: To assess the influence of the COVID-19 pandemic on the incidence, management and outcome of SE patients.