Regulatory and activated effector T cells in chronic hepatitis C virus: Relation to autoimmunity.

Aim: To investigate how Tregs are regulated in chronic hepatitis C virus (HCV) patients assessment of Tregs markers (granzyme 2, CD69 and FoxP3), Teffs markers [TNFRSF4 (OX40), INFG] and , genes.

Methods: A prospective study was conducted on 120 subjects divided into 4 groups: Group I ( = 30) treatment naïve chronic HCV patients; Group II ( = 30) chronic HCV treated with Peg/Riba; Group III ( = 30) chronic HCV associated with non-organ specific autoantibody and Group IV ( = 30) healthy persons as a control group. Tregs and Teffs markers were assessed in peripheral blood mononuclear cells by quantitative real time reverse transcriptase-polymerase chain reaction.

Microwave ablation versus transarterial chemoembolization in large hepatocellular carcinoma: prospective analysis.

Objective: Limited therapies are offered for large hepatocellular carcinoma (HCC). It carries dismal prognosis and efforts tried changing its management from a palliative to a curative mode. Transarterial chemoembolization (TACE) is a palliative procedure that may have survival benefit if compared to non-management of large lesions.