Gingival crevicular fluid levels of prolactin hormone in periodontitis patients before and after treatment and in healthy controls.

Objective: Prolactin (PRL) acts as a hormone and as a cytokine and is linked to the pathogenesis of a variety of chronic inflammatory diseases. This study aimed to investigate a potential role for prolactin in the pathogenesis of periodontitis by assessing its local gingival crevicular levels before and after periodontal treatment, compared to controls.

Materials And Methods: 40 participants were included and divided into 2 groups.

Expression of Leptin and Visfatin in Gingival Tissues of Chronic Periodontitis With and Without Type 2 Diabetes Mellitus: A Study Using Enzyme-Linked Immunosorbent Assay and Real-Time Polymerase Chain Reaction.

Background: The aim of this study is to investigate the protein and gene expression of leptin and visfatin in gingival tissue from patients with chronic periodontitis (CP), patients with CP and type 2 diabetes mellitus (T2DM), and healthy individuals.

Methods: The study includes 50 individuals: 10 healthy individuals, 20 patients with CP, and 20 patients with CP and T2DM. Plaque index, gingival index, probing depth, and clinical attachment loss were measured, and gingival biopsies were obtained.