Publications by authors named "Eman Ibrahim Elzain"
Front Immunol
February 2022
Article Synopsis
- Chronic lung inflammation's link to COVID-19 risk remains debated, with ACE2 and TMPRSS2 receptors playing critical roles in SARS-CoV-2 entry into lung cells.
- In a study of asthmatic patients using established data sets, higher levels of ACE2, and to a lesser extent TMPRSS2, were found in asthmatics compared to healthy individuals, indicating a potential connection between asthma severity and receptor expression.
- The study highlighted that specific inflammatory cytokines regulate the expression of these receptors, with Type I cytokines generally increasing and Type II cytokines decreasing ACE2 levels, suggesting that inflammation type could influence susceptibility to COVID-19 in asthmatics.
