Correction: Alamri et al. Enhancement of the Protective Activity of Vanillic Acid against Tetrachloro-Carbon (CCl) Hepatotoxicity in Male Rats by the Synthesis of Silver Nanoparticles (AgNPs). 2022, , 8308.

In the original publication [...

Developing novel hybrid bilayer nanofibers based on polylactic acid with impregnation of chamomile essential oil and gallic acid-stabilized silver nanoparticles.

This study presents fabrication and characterization of novel chamomile essential oil (CMO)/gallic acid-stabilized silver nanoparticles (gallic acid-nanosilver, GNS), embedded into polylactic acid (PLA)-based hybrid bilayer nanofibers (NFs). Where CMO was impregnated into polyvinyl alcohol (PVA)-polyethylene glycol (PEG) solution and electrospun simultaneously with PLA to obtain PLA/PVA-PEG-CMO NFs (PLA/CMO A2). Meanwhile, GNS were added to PVA-PEG-CMO and electrospun to obtain PLA/PVA-PEG-CMO-GNS NFs (PLA/CMO-GNS A3).

The Protective Effects of Vanillic Acid and Vanillic Acid-Coated Silver Nanoparticles (AgNPs) in Streptozotocin-Induced Diabetic Rats.

The production of nanoparticles enhances the bioactivity of biological molecules for drug delivery to diseased sites. This study explains how silver nanoparticle (AgNP) coating enhanced the protection effects of vanillic acid in male diabetic rats with streptozotocin- (STZ-) induced diabetes. Twenty-four rats were divided into four groups ( = 6) for this investigation.

Nanoemulsions of L. (Decaffeinated) and L. Extracts as a Novel Approach for the Treatment of Carbon Tetrachloride-Mediated Liver Fibrosis.

Liver fibrosis is a condition characterized by the excessive buildup of scar tissue in the liver. This scarring occurs as a result of chronic liver damage, often caused by conditions such as hepatitis, alcohol abuse, certain metabolic disorders, genetic abnormalities, autoimmunity, and noninfectious diseases such as fatty liver which leads to liver fibrosis. Nanoparticles have gained attention in recent years as potential therapeutic agents for liver fibrosis.

Biochemical Assessments of Six Species of Edible Coastal Algae Collected from Tabuk Region in Saudi Arabia.

In the first study focusing on the Red Sea's Tabuk coast, six edible species of the most common algae were collected to evaluate their approximate composition using AOAC methods, amino acids using ion-exchange chromatography, minerals using atomic absorption spectroscopy, phenolic compounds using the Folin-Ciocalteu method, and ferric-reducing antioxidant power. All the data were significantly ( < 0.05) different among all the studied species.

The Hepatic Antisteatosis Effect of Xanthohumol in High-Fat Diet-Fed Rats Entails Activation of AMPK as a Possible Protective Mechanism.

Obesity is the leading cause of non-alcoholic fatty liver disease by provoking hyperglycemia, hyperlipidemia, insulin resistance, oxidative stress, and inflammation. Low activity of AMP-activated protein kinase (AMPK) is linked to obesity, liver injury, and NAFLD. This study involves examining if the anti-steatosis effect of Xanthohumol (XH) in high-fat diet (HFD)-fed rats involves the regulation of AMPK.

Marula oil nanoemulsion improves motor function in experimental parkinsonism mitigation of inflammation and oxidative stress.

Parkinson's disease (PD) is a neurologic condition exhibiting motor dysfunction that affects old people. Marula oil (M-Oil) has been used longley in cosmetics and curing skin disorders. M-Oil is particularly stable due to its high concentration of monounsaturated fatty acids and natural antioxidants.

Response of trees to salinity stress conditions in Tabuk region, Kingdom of Saudi Arabia.

is an amazing tree with various applications. Salinity is a world major barrier to crop productivity. This study was conducted to investigate salinity and seaweed extract's effect on 's growth and yields.

Chemical Constituents, Antioxidant Potential, and Antimicrobial Efficacy of Extracts against Multidrug-Resistant Bacteria.

Aniseeds () have gained increasing attention for their nutritional and health benefits. Aniseed extracts are known to contain a range of compounds, including flavonoids, terpenes, and essential oils. These compounds have antimicrobial properties, meaning they can help inhibit the growth of nasty bacteria and other microbes.

α-Hederin Saponin Augments the Chemopreventive Effect of Cisplatin against Ehrlich Tumors and Bioinformatic Approach Identifying the Role of SDF1/CXCR4/p-AKT-1/NFκB Signaling.

Stromal cell-derived factor-1 (SDF1) and its C-X-C chemokine receptor type 4 receptor (CXCR4) are significant mediators for cancer cells' proliferation, and we studied their expression in Ehrlich solid tumors (ESTs) grown in mice. α-Hederin is a pentacyclic triterpenoid saponin found in Hedera or Nigella species with biological activity that involves suppression of growth of breast cancer cell lines. The aim of this study was to explore the chemopreventive activity of α-hederin with/without cisplatin; this was achieved by measuring the reduction in tumor masses and the downregulation in SDF1/CXCR4/pAKT signaling proteins and nuclear factor kappa B (NFκB).

Soluble guanylate cyclase agonist, isoliquiritigenin attenuates renal damage and aortic calcification in a rat model of chronic kidney failure.

Aims: Chronic kidney disease (CKD) is a growing fatal health problem worldwide associated with vascular calcification. Therapeutic approaches are limited with higher costs and poor outcomes. Adenine supplementation is one of the most relevant CKD models to human.

Enhancement of the Protective Activity of Vanillic Acid against Tetrachloro-Carbon (CCl) Hepatotoxicity in Male Rats by the Synthesis of Silver Nanoparticles (AgNPs).

In the current study, the hepatoprotective activity of vanillic acid, silymarin, and vanillic acid-loaded silver nanoparticles (AgNPs) against CCl-induced hepatotoxicity was tested in male rats for four weeks. Thirty male rats were divided into five groups ( = 6). The 1st group was a negative control, the 2nd group was a positive control, the 3rd group was treated with 100 mg/kg b.

Response of Growth, Yield, and Phytochemical Behavior of Jojoba Genotypes to Plant Extract.

A unique storage lipid wax found in jojoba seeds can be employed as a chemical feedstock. Alternative safe and natural sources of plant nutrients are constantly sought to preserve both human health and the environment. As a result, EAI1, EAI2, and EAI3 jojoba genotypes' growth, yield, and phytochemical behavior in response to Azolla extract at concentrations of 0, 10, and 30% were studied.

Fermented Hass avocado kernel: Nutritional properties and use in the manufacture of biscuits.

In this study, the use of fermented Hass avocado kernel (FHK) with to produce functional biscuits was examined. The chemical composition and antinutrient factors were evaluated for raw and fermented Hass avocado kernels. Fatty acids were separated by gas liquid chromatography.

A study of chemical Composition, Antioxidants, and volatile compounds in roasted Arabic coffee.

(Rubiaceae) is a basic drink for all Gulf societies, especially Saudi Arabia, it is the main part of the Saudi tradition. This investigation was carried out to track the chemical composition, caffeine content by UV-visible spectrophotometer, acrylamide content by using a gas chromatograph, free radical scavenging capacity by DPPH methods as well as determined the browning index and separated the volatiles compounds using GC-MS for the most common three degree of roasted Arabic coffee; light (180 ± 10 °C; 6.0 ± 1.

Saponin-rich extract of Tribulus terrestris alleviates systemic inflammation and insulin resistance in dietary obese female rats: Impact on adipokine/hormonal disturbances.

Tribulus terrestris saponins (TTS) have been longley used as an overall tonic and recent studies showed they influence inflammatory conditions. We examined the ameliorative effect of a commercial formula of a saponin-rich extract of TT in a model of dietary obesity in female rats focusing on their ability to control the inflammatory burden, insulin resistance (IR), adipokine expression and the related reproductive system pathologies. Female rats were fed with high fat diet (HFD) for 14 weeks to launch diet-induced obesity; they were assigned as: the obese control female rats (OFR) which received no treatment and TTS (5 and 10 mg/kg/day) treated rats; they were compared to a normal rat group.

Maximizing Leaves, Inflorescences, and Chemical Composition Production of Trees under Calcareous Soil Conditions.

One of the main issues limiting plant productivity is a lack of soil nutrient resources, especially in calcareous soil, which covers more than one third of the world's land surface area. On the other hand, despite rising demand for all parts of the tree, several studies have focused on its leaf production as an herbaceous plant, rather than as a tree, and no extensive research has been carried out on leaf and inflorescence production in the mature tree. As a result, the influence of vermicompost and NPK (minerals and nanoparticles), as well as their combination, under calcareous soil conditions, was investigated in this study.

Effects of COVID-19 home confinement on eating behavior: A review.

Coronavirus disease is a global pandemic that has led to radical changes in lifestyle habits, including dietary habits. Therefore, the objective of the present review is to evaluate the effect of quarantine on dietary habits when enforcing a lockdown. Some databases were used, including Web of Science, Science Direct, Google Scholar, and PubMed.

Relationships among consanguinity, family history, and the onset of type 1 diabetes in children from Saudi Arabia.

Aims: We aimed to demonstrate the relationship between parental consanguinity and positive family histories of type 1 diabetes mellitus (T1DM) and autoimmune disease and the development of T1DM among children in Saudi Arabia.

Methods: This was a cross-sectional case-control study. In total, 192 patients and 188 healthy controls were enrolled from the Pediatric Diabetes Clinic at King Salman Military Hospital between January 2000 and December 2010.

Efficacy of gluten- and casein-free diets on autism spectrum disorders in children.

Food containing gluten and casein could play a role in autism spectrum disorders (ASD) symptoms. The present review aimed to update the evidence about the role of the gluten- and casein-free diet (GCFD) on the management of ASD. Web of Science, Science Direct, Google Scholar, and PubMed databases were used to search for randomized controlled trials (RCT) conducted between January 2000 and February 2020.

The association between the timing of energy intake and the risk of overweight and obesity among Saudi female university student.

To investigate the relationship between the timing of energy intake and obesity. Methods: A cross-sectional study was conducted between September 2018 and December 2018. A total of 450 Saudi female students from the University of Tabuk, Tabuk, Saudi Arabia were recruited.