APOE Gene polymorphism among Jordanian Alzheimer`s patients with relation to lipid profile.

Objective: To investigate the frequencies of the apolipoprotein E (APOE) alleles and genotypes and study their relationship with the lipid profile in Jordanian patients with late-onset Alzheimer`s disease (AD).

Methods: This case-control study was carried out on 71 Jordanian individuals: 38 patients with late-onset AD (age >/=65 years) and 33 age-matched healthy controls. All participants were recruited from senior homes and Jordan University Hospital, Amman, Jordan between January 2010 and December 2013.

Relation between uric acid and Alzheimer's disease in elderly Jordanians.

Background: It has been suggested that oxidative injuries have a role in the pathogenesis of Alzheimer's disease (AD). Uric acid (UA) has a contradictory effect on cognitive function and several lines of evidence suggest that UA may modulate outcome in neurological diseases.

Objectives: Many studies investigated serum UA levels in AD patients, but to date, results from these observational studies are conflicting.

Relation between copper, lipid profile, and cognition in elderly Jordanians.

The purpose of the current study was to examine the association of serum copper and lipid concentrations with changes in cognitive function in elderly Jordanian individuals. The study population consisted of two groups: 52 dementia patients and 50 control subjects. All individuals were screened using the Mini-Mental State Examination and Clock Drawing Test.