Publications by authors named "Eman Al Yemni"
Article Synopsis
- - Researchers explored rare genetic changes, specifically single nucleotide variants (SNVs), to understand their potential contribution to Attention Deficit Hyperactivity Disorder (ADHD) in families from a high-consanguinity population.
- - Using whole exome sequencing, they identified 32 rare variants across 31 genes linked to ADHD, many of which hadn't been previously associated with the disorder or other human conditions.
- - Their analysis suggested that the affected genes are involved in important brain functions, particularly those related to glutamatergic synapses and cytoskeleton organization, reflecting the complex genetic nature of ADHD.
Genetic studies of the familial forms of Parkinson's disease (PD) have identified a number of causative genes with an established role in its pathogenesis. These genes only explain a fraction of the diagnosed cases. The emergence of Next Generation Sequencing (NGS) expanded the scope of rare variants identification in novel PD related genes.
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- The study focuses on identifying genetic factors linked to Attention Deficit Hyperactivity Disorder (ADHD) through analysis of families with multiple affected members in Saudi Arabia, suggesting the genetic complexity of ADHD hinders risk-gene identification.* -
- Researchers analyzed 41 individuals from these families, discovering multiple shared genomic regions across various chromosomes, particularly highlighting chromosomes 8 and 17 as significant.* -
- Findings emphasize the potential relevance of specific genes related to neurotransmission and immune response in ADHD, offering new insights into the genetic diversity of the disorder, particularly in an understudied population.*