In neonates with vitamin D deficiency, low lymphocyte activation markers are risk factors for infection.

: Vitamin D has regulatory effects on different cells of the immune system and low levels are associated with several immune-mediated diseases. : To investigate the association between neonatal 25-hydroxy vitamin D (25-OHD) level and the expression of lymphocyte activation markers (HLA-DR, CD69, CD25, CD45RA) on T-lymphocyte subpopulations and its impact in neonatal infection. : 25-OHD level was measured in the cord blood of 56 neonates and their mothers using an enzyme immune-assay method.

Growth Parameters and Vitamin D status in Children with Thalassemia Major in Upper Egypt.

Aim: The aim of this study is to assess the growth parameters, vitamin D, calcium, and phosphorous status in children with thalassemia major receiving packed red cells transfusion with chelation therapy.

Patients And Methods: In a case control study, 100 patients with beta thalassemia major (aged from 4 to 15 years) were compared with 100 sex- and age-matched children serves as a control group. Anthropometric measurement, Serum level of calcium, phosphorus and vitamin D (25 hydroxycholecalciferol) were estimated for all patients & controls.