Assessment of Anti-carcinogenic Effect of Pomegranate in Oral Squamous Cell Carcinoma (Pre-clinical Study).

Background And Objective: The survival portion of patients treated from oral cancer isn't in progress. This is why researchers are continuously looking for new anti-cancer drugs either natural product or natural product derivatives. Studies have shown that pomegranate and its constituents might have an anti-tumorigenic effect.

Pulpal repair after direct pulp capping with new bioceramic materials: A comparative histological study.

Aim: To histopathologically evaluate the pulpal healing after direct pulp capping with TotalFill and compared it with Neo MTA Plus in human tooth cultures.

Methods: Forty sound human premolars freshly extracted for orthodontic reasons were randomly assigned to two experimental groups; group I: TotalFill and group II: Neo MTA Plus. Standardized Class V cavities were prepared on the buccal surface of each tooth where the pulp exposure was performed with a dental explorer.

ALK1 expression in oral lichen planus: a possible relation to microvessel density.

Objective: To assess the expression of activin receptor-like kinase 1 (ALK1) and investigate its possible relationship with microvessel density (MVD) in different forms of oral lichen planus (OLP) compared to controls' biopsies.

Methods: Biopsies from 20 reticular/papular OLP (R/PLP), 20 atrophic/erosive OLP (A/ELP) patients, and 20 healthy subjects were immunohistochemically analyzed and statistically compared and correlated for ALK1 expression and MVD as assessed by CD34 expression.

Results: All OLP specimens revealed the presence of positive cytoplasmic CD34 immunostaining in endothelial cells, with statistically high significant MVD in each of R/PLP (Median; M = 4.

Influence of alendronate administration regimen on the final outcome of implant osseointegration in an osteoporotic model.

This study aimed to evaluate the bone response around titanium implants in osteoporotic rabbits receiving oral alendronate (ALN) for one month either simultaneously with implant placement (IP) or stopped immediately before surgery. Six weeks before IP, 34 adult female New Zealand white rabbits were submitted to intramuscular injections of dexamethasone (3 mg/kg twice a week) to induce osteoporosis-like conditions. Two animals were sacrificed and histological examinations of their leg bones were performed to confirm the osteoporosis-like condition, as compared to a healthy animal.

Evaluation of neoplastic nature of keratocystic odontogenic tumor versus ameloblastoma.

Objective: Although most of odontogenic tumors are benign, some of them will show locally destructive behavior, as keratocystic odontogenic tumor (KCOT) is now known as a benign but aggressive odontogenic neoplasm. The neoplastic characteristics in KCOT have been suggested from clinical as well as pathologic aspects. Matrix metalloproteinase-2 (MMP-2) is a gelatinase form of the MMPs family, which is a group of proteolytic enzymes that degrade many types of collagen.

Genotoxic effects of dental panoramic radiograph in children.

Unlabelled: This study was completed to evaluate chromosomal damage (micronucleus) and cellular death in exfoliated buccal mucosa cells taken from healthy children following exposure to panoramic radiation during dental radiography.

Method: Twenty children who underwent panoramic dental radiography for diagnostic purposes were included. Cytological preparations were stained with Feulgen stain, identified under light microscopy.

Differential expression of c-kit and CD43 in histological subtypes of adenoid cystic carcinoma of salivary gland.

Unlabelled: Adenoid cystic carcinoma (ACC) of the salivary gland is characterized by a prolonged but inevitably unfavorable clinical course. Recent studies have suggested that the transmembrane tyrosine kinase receptor, c-kit proto-oncogene is involved in ACC pathogenesis. CD43 is a sialoglycoprotein that is typically expressed by hematopoietic cells and their derivative neoplasms, although positivity in epithelial tumors has only been recognized recently.

Exploration of the histogenesis of congenital granular cell epulis: an immunohistochemical study.

Objective: Congenital granular cell epulis is a benign soft tissue lesion of the neonate that arises from the alveolar ridges of the jaws in newborns. The aim of this study is to define the histogenesis of congenital granular cell epulis by using several immunohistochemical markers.

Materials And Methods: A series of six cases of congenital granular cell epulis were immunostained with a panel of antibodies (NSE, CD68, CD99, Mesothelin, Inhibin-a, GFAP, Dystrophin, NGFR/p75 and TLR1).