Protective effect of -butylhydroquinone against cisplatin-induced hepatorenal injury via modulating oxidative stress, inflammation, and apoptosis.

Context: Cisplastin (CDDP) is a chemotherapeutic drug frequently used to manage a variety of cancers. However, its use is associated with hepatorenal toxicity resulting from elevated reactive oxygen species production.

Objective: Herein, the hepatorenal protective effect of -butylhydroquinone (tBHQ) in cisplatin (CDDP)-treated rats was examined.