Pro-inflammatory versus anti-inflammatory cytokines in psoriatic patients (case-control study).

Background: Psoriasis (PsO) is a systemic autoimmune disease. Many pro-inflammatory and anti-inflammatory biomarkers have been associated with the pathogenetic process of psoriasis. IL-35 act as an anti-inflammatory cytokine through downregulation of TH-17 cell development and cytokine production.

Intralesional vitamin D3 in treatment of alopecia areata: A randomized controlled clinical trial.

Background: Alopecia areata (AA) is a common non-scarring, inflammatory type of hair loss that affects people of all ages and genders.

Aims: To evaluate the safety and efficacy of intralesional vitamin D3 injection in the treatment of alopecia areata.

Patients And Methods: A randomized controlled clinical trial included a total of 60 adult patients with localized alopecia areata were randomly assigned into two groups.