Synthesis, spectroscopic characterization and biological activities of complexes of light lanthanide ions with 3-hydroxyflavone.

New solid compounds of light lanthanide ions with 3-hydroxyflavone were synthesized in good yields (up to 85 %). The resulting complexes have been thoroughly characterized using various analytical and spectral techniques, including elemental analysis, complexometry, thermogravimetry, UV-VIS, FT-IR, H NMR, AgNPET LDI MS and fluorescence spectroscopy. The molecular formulas of the complexes were determined as follows: Ln(3HF), where 3HF-3-hydroxyflavone, Ln = La(III), Pr(III), Nd(III) and Ln(3HF)·nHO, where n = 1 for Ln = Ce(III), Sm(III), Eu(III), and n = 2 for Gd(III).

Existential Loneliness Among Older People from the Perspective of Health Care Professionals: A European Multicenter Study.

Introduction: Health care professionals (HCPs) encounter different forms of loneliness in their work. It is essential that they have the courage, skills, and tools to deal with loneliness, in particular with existential loneliness (EL) which relates to meaning in life and the fundamentals of living and dying.

Aim: The aim of this study was to investigate HCPs' views on loneliness among older people and their understanding, perception, and professional experience of EL in older people.

Syntheses, crystal structures and antioxidant study of Zn(II) complexes with morin-5'-sulfonic acid (MSA).

The study of modified synthetic procedure of water soluble morin-5'-sulfonic acid sodium salt (NaMSA) involving less aggressive chemicals and carried out at mild conditions was described. The NaMSA salt is a convenient source of anionic morin-5'-sulfonic ligand (MSA) in ion exchange reactions. The coordination ability of MSA ligand towards the zinc cations was investigated in aqueous solution and in solid state.

Tautomeric and Microscopic Protonation Equilibria of Anthranilic Acid and Its Derivatives.

The acid-base chemistry of three zwitterionic compounds, namely anthranilic (2-aminobenzoic acid), -methylanthranilic and -phenylanthranilic acid has been characterized in terms of the macroconstants , , the isoelectric point p, the tautomerization constant and microconstants , , , . The potentiometric titration method was used to determine the macrodissociation constants. Due to the very poor water solubility of -phenylanthranilic acid the dissociation constants p and p were determined in MDM-water mixtures [MDM is a co-solvent mixture, consisting of equal volumes of methanol (MeOH), dioxane and acetonitrile (MeCN)].

Comparative study on the antibacterial activity of some flavonoids and their sulfonic derivatives.

The antibacterial activity of quercetin, morin, sodium salt of quercetin-5'-sulfonic acid (NaQSA) and sodium salt of morin-5'-sulfonic acid (NaMSA) were tested against six bacterial strains: Escherichia coli (ATCC 25922 and clinical isolates--ESBL), Pseudomonas aeruginosa (ATCC 27853 and clinical isolates--carbapenem resistant), Staphylococcus aureus (ATCC 29213 and clinical isolats- MRSA). The most effective inhibitors against the model strain S. aureus are NaQSA and NaMSA (MIC = 3.

New complexes of La(III), Ce(III), Pr(III), Nd(III), Sm(III), Eu(III) and Gd(III) ions with morin.

New solid complex compounds of La(III), Ce(III), Pr(III), Nd(III), Sm(III), Eu(III) and Gd(III) ions with morin were synthesized. The molecular formula of the complexes is Ln(C(15)H(9)O(7))(3).nH(2)O, where Ln is the cation of lanthanide and n=6 for La(III), Sm(III), Gd(III) or n=8 for Ce(III), Pr(III), Nd(III) and Eu(III).

Antibacterial activity of morin and its complexes with La(III), Gd(III) and Lu(III) ions.

The antibacterial activity of morin, sodium salt of morin-5"-sulfonic acid (NaMSA) and new complexes of La (II), Gd (III) and Lu (III) with morin were tested against three bacterial strains: Escherichia coli G (-), Klebsiella pneumoniae G (-), Staphylococcus aureus G (+) and compared with the activity of penicillin. All of the complexes possess inhibitory action against the tested strains. The activity of the studies compounds depends on their concentration.