Publications by authors named "Elzbieta Wisniewska"
Hum Immunol
September 2012
Article Synopsis
- Non-small cell lung carcinoma (NSCLC) is influenced by environmental and genetic factors, and this study focused on the role of killer immunoglobulin-like receptor (KIR) genes and their ligands in NSCLC susceptibility and treatment response.
- KIR genes were not linked to NSCLC, but specific gene combinations, particularly C1C1 homozygotes, were more frequent in NSCLC patients than healthy controls.
- Patients with KIR2DL2 and KIR2DS2 genes who were also homozygous for the C1 ligand showed a significantly better treatment response and longer median survival (23 months) compared to those with different genotypes (10 months).
