Thymic E4bp4 gene transcription is up-regulated in the chicken during experimental peritonitis modified by the season-related lighting conditions.

Immunity, like other vertebrate processes, undergoes the diurnal and seasonal rhythmicity generated and synchronized by the endogenous clock. In the present study a transcription of the selected clock genes was evaluated in the chicken thymus to verify its supposed role as a peripheral clock and to check its relation with the seasonality of immune function. Chickens kept from hatch in the season-related lighting conditions (LD 16:8 in summer vs 8:16 in winter) and in a controlled temperature were exposed to the experimental peritonitis elicited by i.

Seasonal postembryonic maturation of the diurnal rhythm of serotonin in the chicken pineal gland.

Previously, we have demonstrated the postembryonic development of chicken (Gallus gallus domesticus L.) pineal gland functions expressed as changes in melatonin (MEL) biosynthesis. Pineal concentrations of MEL and its precursor serotonin (5-HT) were shown to increase between the 2nd and 16th day of life.

Pineal oscillator functioning in the chicken--effect of photoperiod and melatonin.

The avian pineal gland, apart from the hypothalamic master clock (suprachiasmatic nuclei, SCN) and retina, functions as an independent circadian oscillator, receiving external photic cues that it translates into the rhythmical synthesis of melatonin, a biochemical signal of darkness. Functional similarity to the mammalian SCN makes the avian pineal gland a convenient model for studies on biological clock mechanisms in general. Pineal melatonin is produced not only in a light-dependent manner but also remains under the control of the endogenous oscillator, while the possible involvement of melatonin in maintaining cyclic expression of the avian clock genes remains to be elucidated.