Long-Term Use of Contributes to Homeostasis in Acne-Prone Skin-A 12-Month Follow-Up International "Real Life" Cohort Study.

Background: Homeostasis in the differentiation programme of sebaceous stem cells has been identified as a key step in comedogenesis and should be a target for acne-prone skin care.

Objective: To report on a multicentre, year-long/real-life use study of a patented natural product containing proven to modulate molecular actors in the initial steps of comedogenesis.

Methods: An open-label multicentric international study, with a 12 month follow-up, included 54 teenage and young adult subjects with mild to moderate facial acne.

Dermoscopy of Small Diameter Melanomas with the Diagnostic Feasibility of Selected Algorithms-A Clinical Retrospective Multicenter Study.

Objective: The aim of the study was to verify two hypotheses. The first concerned the possibility of diagnostic dermoscopic differentiation between cutaneous melanomas of the histopathological category in situ (pTis) and thin melanomas (pT1a) in terms of their diameter. The second assessed the diagnostic feasibility of two dermoscopic algorithms aiming to detect ≤ 5.

Epidemiology of atopic dermatitis in Europe.

Atopic dermatitis (AD) is a chronic inflammatory disease persisting predominantly in the pediatric population. Its development is most presumably multifactorial and a derivative of interplay between genetic, immunologic, and environmental causes. To the authors' knowledge, no multinational and systematic database of AD prevalence is established and maintained for Europe.

Comparison of treatment standards in Atopic Dermatitis management across selected geographies prior to emerging targeted therapies onset.

Atopic Dermatitis (AD) is a chronic inflammatory disease persisting predominantly in the pediatric population. Treatment is generally supervised by various medical specialists, including primary care practitioners, allergists, and dermatologists. This divergence in disease management allows various therapeutic approaches to be administered to patients by supervised physicians.

New indications for topical ivermectin 1% cream: a case series study.

Introduction: Topical ivermectin is an effective treatment for inflammatory papulopustular rosacea in adults. Positive therapeutic effects of ivermectin due to its potential anti-inflammatory properties could be achieved in the other facial dermatoses.

Aim: To assess the efficacy of topical ivermectin 1% cream therapy in mild and moderate perioral dermatitis (PD), seborrheic dermatitis (SD) and acne vulgaris (AV).

Hair shaft videodermoscopy in netherton syndrome.

Netherton syndrome is an autosomal recessive disorder, characterized by ichthyosis, atopic manifestations, and hair shaft abnormalities (trichorrhexis invaginata). The diagnosis of Netherton syndrome may be established on the basis of just one abnormal hair, but it is often difficult to find a hair with pathognomonic features on light microscopic examination. Every attempt requires pulling new hairs.

Dermoscopy in female androgenic alopecia: method standardization and diagnostic criteria.

Objective: Establishing the trichoscopy criteria of female androgenic alopecia (FAGA).

Design: Trichoscopy images were retrospectively evaluated.

Setting: Dermatologic hospital-based clinic and private practice offices.

Comma hairs: a dermatoscopic marker for tinea capitis: a rapid diagnostic method.

Background: Dermatoscopy and videodermatoscopy have been used for several years in the diagnosis of skin disorders.

Objective: We sought to determine whether tinea capitis (TC) shows characteristic videodermatoscopy features that may facilitate its differentiation from alopecia areata (AA).

Methods: Two patients with TC caused by Microsporum canis, confirmed by mycological culture and fluorescence under Wood lamp, were examined with videodermatoscopy and results were compared with videodermatoscopy results of 12 patients with AA.

Trichoscopy: a new method for diagnosing hair loss.

Videodermoscopy of hair and scalp (trichoscopy) is gaining popularity as a valuable tool in differential diagnosis of hair loss. This method allows viewing of the hair and scalp at X20 to X160 magnifications. Structures which may be visualized by trichoscopy include hair shafts of different types: vellus, terminal, micro-exclamation mark type, monilethrix, Netherton type, and pili annulati hairs.

Trichoscopy in genetic hair shaft abnormalities.

Background: Diagnosis of hair shaft abnormalities is based on light microscopic examination of more than 50 plucked hairs. The aim of this study was to verify whether hair shaft abnormalities may be visualized by trichoscopy (hair and scalp videodermoscopy) and to analyze trichoscopic features of common genetic hair shaft dysplasias.

Method: Patients with known genetic hair shaft disorders were included into the study.

Cylindroma transforming into basal cell carcinoma in a patient with Brooke-Spiegler syndrome.

Background: Brooke-Spiegler syndrome is a rare condition with a predisposition to develop cutaneous adnexal neoplasms, especially cylindromas, trichoepitheliomas and spiradenomas. Malignant transformation of cylindromas is rare. In such cases usually cylindrocarcinomas develop within these lesions.