Publications by authors named "Elyes Majoul"
Hydroxycarbamide, available as tablets, is a pharmacological agent for fetal hemoglobin induction such as sickle cell anemia. The need for alternative dosage form options for patients unable to take tablets led hospital pharmacies to prepare solutions and suspensions. The objective of this study was to determine the stability of hydroxycarbamide in Ora-Plus in combination with either Ora-Sweet or Ora-Sweet SF, Ora-Blend, or Ora-Blend SF suspending agents.
View Article and Find Full Text PDFA stability-indicating assay by reversed-phase high performance liquid chromatography method was developed and validated for the determination of sulthiame (STM). The chromatographic separation was achieved on a reversed-phase NovaPack C18 column and an isocratic mobile phase consisting of deionized water:methanol (70:30, v/v). The flow rate was 1.
View Article and Find Full Text PDFAdapted forms for administration to infants are limited. The proposed study was performed to propose oral liquid formulations of idebenone in Ora-Plus and either Ora-Sweet or Ora-Sweet SF, Ora-Blend, Ora-Blend SF and Inorpha. Each formulation was stored in 30 ml amber glass bottle at 5 or 25 °C for 90 days.
View Article and Find Full Text PDFArticle Synopsis
- The study aimed to evaluate how implementing Computerized Physician Order Entry (CPOE) combined with pharmacist checks affects medication errors in an orthopaedic surgery unit during the prescribing, dispensing, and administration phases.
- An observational study monitored medication errors before and after CPOE implementation in a Paris hospital, observing 111 patients before and 86 after, analyzing error frequencies across the three stages of drug management.
- Results showed a dramatic 92% reduction in prescribing errors and a 17.5% decrease in administration errors due to CPOE, while dispensing errors did not significantly change, indicating that CPOE improves drug management safety and quality.