Publications by authors named "Elvira Verhoef"
EMBO Mol Med
December 2022
Article Synopsis
- Spontaneous bleeds are a major cause of mortality in children with Alagille syndrome (ALGS), particularly affecting girls more than boys, as shown by a systematic review of vascular events.
- Research using Jag1 mouse models revealed they experienced vascular abnormalities, including brain bleeds and blood vessel issues, which could exacerbate with high blood pressure.
- Retinography was found to be an effective non-invasive tool for examining vascular characteristics in ALGS patients, highlighting significant sex differences in vascular conditions in this disorder.
