Evaluation of Mutational Status in Liquid Biopsy to Monitor Disease Progression in Metastatic Colorectal Cancer Patients.

In this study we evaluated both~ K- and N- mutations in plasma samples from patients with metastatic colorectal cancer by means of the BEAMing technology, and we assessed their diagnostic performance compared to analyses performed on tissue. The sensitivity of BEAMing in identifying mutations was of 89.5%, with a fair specificity.