Retinal Nerve Fiber Layer Thickness Alterations after Electroconvulsive Therapy in Patients with Mental Illness.

Background: We hypothesized that the ongoing neurotrophic effects of electroconvulsive therapy (ECT) might be detected in the retinal nerve fiber layer (RNFL) using optical coherence tomography (OCT).

Methods: This study was conducted using a prospective design. The RNFL thickness alterations of 18 psychiatric patients undergoing ECT were assessed using OCT.