Publications by authors named "Elton Yamaguchi"
Article Synopsis
- The study focuses on sleep disorders in patients with spinocerebellar ataxia type 3 (Machado-Joseph disease), specifically restless legs syndrome and rapid eye movement sleep behavior disorder, and examines the link with dopamine transporter (DAT) densities.
- Twenty-two MJD patients and twenty healthy subjects participated, undergoing clinical evaluations, polysomnography, and DAT imaging via SPECT.
- Results indicated that MJD patients had significantly lower DAT densities compared to controls, but no correlation was found between DAT levels and sleep disorders, suggesting other dopamine pathways may play a role in MJD-related sleep issues.
Multiple sclerosis (MS) is a chronic autoimmune demyelinating disease of the central nervous system that causes neurological disorders in young adults. Previous studies in various populations highlighted an association between the HLA-DRB1*15 allele and MS. This study investigated the association between HLA-DRB1*15 and other HLA-DRB1 alleles and MS in a Brazilian Caucasian population sample from Londrina, Southern Brazil.
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