Rationale: When diagnosed with cancer, a patient has to cope with stressors such as pain, fatigue, and the experience of life-threat that can cause great distress. Spirituality may be a resource for coping with these problems, thereby reducing distress.
Objective: Two questionnaire studies-the first a cross-sectional (Study 1; N = 216) and the second a one-year longitudinal (Study 2; N = 383)-investigated among Dutch cancer patients whether spirituality lessens the impact of pain, fatigue, and perceived life-threat on distress.