Obesity as a modifying factor of periodontal therapy outcomes: local and systemic adipocytokines and oxidative stress markers.

Objectives: Adipocytokines and oxidative stress (OS) are involved in the pathogenesis of both obesity and periodontitis. The aim of this study was to evaluate periodontal therapy outcomes in terms of serum and gingival crevicular fluid (GCF) levels of adipocytokines and OS markers in obese patients with periodontitis, in order to have an insight into the association between obesity and periodontitis.

Materials And Methods: A total of 39 patients (20 obese, 19 non-obese) with periodontitis were included in this study.

The influence of diabetes mellitus on the peri-implant microflora: A cross-sectional study.

Background: Type 2 diabetes mellitus (T2DM) is an important systemic disease, predisposing patients to inflammatory conditions including periodontitis and peri-implantitis and negatively affects dental implant success through various mechanisms. This study aimed to compare clinical and microbiological findings of individuals with dental implants with or without T2DM.

Methods: A total of 82 dental implants which were in function >3 years, were involved.

Evaluation of long-term effects of diode laser application in periodontal treatment of poorly controlled type 2 diabetic patients with chronic periodontitis.

Purpose: This study aimed to investigate the effects of diode laser (DL) in addition to non-surgical periodontal treatment on periodontal parameters, systemic inflammatory response and serum haemoglobin A (HbA ) level in patients with poorly controlled type 2 diabetes mellitus (T2DM) and chronic periodontitis.

Methods: Thirty-seven patients with poorly controlled T2DM and chronic periodontitis completed this study. The patients were divided into two groups.

Evaluating clinical and laboratory effects of ozone in non-surgical periodontal treatment: a randomized controlled trial.

Objective: This study aims to evaluate the clinical and biochemical (oxidative stress and pro-inflammatory mediators) effects of the gaseous ozone use accompanied by scaling and root planning (SRP) in periodontal treatment.

Material And Methods: The study population consisted of 40 patients with chronic periodontitis (CP) randomly sorted into two groups of 20. The experimental group received SRP plus 3 watts gaseous ozone in two separate applications five days apart, whereas the control group received SRP plus placebo.

Effects of diode laser application on inflammation and mpo in periodontal tissues in a rat model.

Objective: In this study, we aimed to histologically and immunologically evaluate the effect of diode laser treatment when applied adjunctive to scaling and root planing (SRP) in an experimental periodontitis model.

Materials And Methods: We used Wistar-Albino rats (n=60) with average weight of 230 g. Experimental periodontitis was induced by ligature at the right and left first mandibular molar teeth in all rats.

Dietary arginine silicate inositol complex inhibits periodontal tissue loss in rats with ligature-induced periodontitis.

The purpose of this study was to induce experimental periodontitis in rats previously fed diets containing arginine silicate inositol (ASI) complex and examine the biochemical, immunological, and radiological effects. Fifty two 8-week-old female Sprague Dawley rats were equally divided into four groups. The control group included those fed a standard rat diet with no operation performed during the experiment.

Association of Oral Health-related Quality of Life with Periodontal Status and Treatment Needs.

Purpose: To evaluate the association of oral health-related quality of life (OHRQoL) with periodontal parameters and treatment needs in a Turkish population and compare the OHRQoL of patients with gingivitis and periodontitis.

Materials And Methods: The present study had a cross-sectional design. The study population consisted of 404 patients with periodontitis (n = 130), gingivitis (n = 141) or periodontal health (n = 133).

The effect of periodontal treatment in improving erectile dysfunction: a randomized controlled trial.

Objective: The aim of the study was to evaluate changes in the International Index of Erectile Dysfunction (IIEF) score following periodontal treatment in patients who had severe or moderate erectile dysfunction (ED) and chronic periodontitis (CP).

Materials And Methods: The authors declare that they have no conflict of interest. The study population consisted of 120 patients with severe or moderate ED and CP.

Is there a relationship between chronic periodontitis and erectile dysfunction?

Introduction: Chronic periodontitis (CP) is characterized with inflammation of the gingival tissues, which causes endothelial dysfunction in different organs.

Aim: In this study, we investigated the association of CP with the erectile dysfunction (ED).

Methods: The study group included 80 male patients with ED and 82 male patients without ED (control), aged between 30 and 40 years.

Effects of low-level laser therapy as an adjunct to standard therapy in acute pericoronitis, and its impact on oral health-related quality of life.

Objective: The purpose of this study was to evaluate the effect of low-level laser therapy (LLLT) as an adjunct to standard therapy in acute pericoronitis.

Methods: Eighty acute pericoronitis patients were randomly assigned to one of four LLLT groups: (neodymium:yttrium-aluminum garnet [Nd:YAG] 1064-nm: n=20, 8 J/cm2, 0.25 W, 10 Hz, 10 sec; 808-nm diode: n=20, 8 J/cm2, 0.

Evaluation of oral health-related quality-of-life in patients with generalized aggressive periodontitis.

Objective: This study aimed to assess the association between the quality-of-life and clinical parameters in patients with generalized aggressive periodontitis.

Materials And Methods: The examination included assessing the number of missing teeth; the number of mobile teeth; and periodontal measures such as bleeding on probing (BoP), probing depth (PD), gingival recession (REC) and plaque index (PI). Patients were asked to rate the impact of their oral health on 16 key areas of oral health-related quality-of-life (OHQoL-UK(©)).

Clinical effects of Nd:YAG laser applications during nonsurgical periodontal treatment in smoking and nonsmoking patients with chronic periodontitis.

Objective: The purpose of this study was to compare the clinical efficacy of nonsurgical periodontal treatment with and without Nd:YAG laser (NDL) applications in smoking and nonsmoking patients with moderate chronic periodontitis (CP).

Materials And Methods: The study population consisted of 52 patients with generalized moderate CP. The study compared the clinical effects of scaling and root planing (SRP) and SRP plus NDL in periodontal pockets measuring between 4 and 6 mm of smoking and nonsmoking patients with CP.

Assessment of oral health in peritoneal dialysis patients with and without diabetes mellitus.

The incidence of chronic renal failure continues to rise worldwide, and although the oral and dental changes in individuals with this condition have been examined, investigations with diabetic peritoneal dialysis (PD) patients are limited. We therefore examined salivary pH, dry mouth, taste change, and mucosal ulceration in diabetic and nondiabetic uremic patients receiving PD. A total of 49 patients undergoing PD therapy were allocated to either the diabetic or the nondiabetic group.

Effect of 1,064-nm Nd:YAG laser therapy on GCF IL-1β and MMP-8 levels in patients with chronic periodontitis.

The aim of this study was to evaluate the long-term effects of a combined periodontal treatment of scaling and root planing (SRP) and Nd:YAG laser (NDL) in chronic periodontitis (CP) patients. This was accomplished by determining the periodontal indices and the interleukin-1beta (IL-1β) and matrix metalloproteinase-8 (MMP-8) levels of the gingival crevicular fluid (GCF). This study was performed according to a random split-mouth-design, controlled clinical trial for sulcular debridement on 40 teeth from 20 patients with generalized moderate chronic periodontitis.

Does peritoneal dialysis affect halitosis in patients with end-stage renal disease?

Objective: There are various causes of halitosis, one of which is chronic renal failure. The objective of this study was to investigate halitosis levels in end-stage renal disease (ESRD) patients before and after peritoneal dialysis (PD) therapy.

Methods: 42 subjects with ESRD were included in this study.

Increased salivary level of 8-hydroxydeoxyguanosine is a marker of premature oxidative mitochondrial DNA damage in gingival tissue of patients with periodontitis.

Introduction: Oxidative stress may contribute to the pathogenesis of periodontitis. However, the detailed molecular mechanism remains unclear. Both 8-hydroxydeoxyguanosine (8-OHdG) and mitochondrial DNA (mtDNA) deletion have been reported as early oxidative DNA damage markers.

Total antioxidant capacity and antioxidant enzymes in serum, saliva, and gingival crevicular fluid of preeclamptic women with and without periodontal disease.

Background: The aim of this study was to investigate the total antioxidant capacity, superoxide dismutase and glutathione peroxidase activities, and malondialdehyde levels in serum, saliva, and gingival crevicular fluid (GCF) in preeclamptic and normotensive pregnant women with and without periodontal disease.

Methods: Forty pregnant women, consisting of 10 preeclamptic subjects with periodontal disease, 10 preeclamptic periodontally healthy subjects, 10 normotensive subjects with periodontal disease, and 10 normotensive periodontally healthy subjects, were included in this study. After clinical measurement and samplings, total antioxidant capacity, superoxide dismutase, glutathione peroxidase activities, and malondialdehyde levels in serum, saliva, and GCF of preeclamptic and normotensive pregnant women were determined, and the data were tested by non-parametric tests.

The Effect of ABO Blood Types on Periodontal Status.

Objectives: The purpose of the present study was to determine whether there was a relationship between periodontal diseases and ABO blood groups.

Methods: This epidemiological study was carried out on 1351 subjects who were randomly selected from individuals referred to the Faculty of Dentistry clinics for periodontal treatment or for other reasons regarding dental health. The study based on periodontal condition, blood group, and medical history.

Periodontal disease increases the risk of severe pre-eclampsia among pregnant women.

Aim: To evaluate the possible link between the severity of periodontal disease and pre-eclampsia and to correlate this link to clinical periodontal parameters and interleukin (IL)-1beta, tumour necrosis factor-alpha (TNF-alpha), and prostaglandins (PGE(2)) levels in both gingival crevicular fluid (GCF) and serum.

Material And Methods: Fifty-nine pregnant women (20 mild pre-eclampsia, 18 severe pre-eclampsia, and 21 healthy pregnant women) were included in the study. Dental and periodontal recordings as well as GCF and blood samples were obtained within 48 h preceding delivery.