Ammonia-oxidizing archaea and bacteria differentially contribute to ammonia oxidation in soil under precipitation gradients and land legacy.

Background: Global change has accelerated the nitrogen cycle. Soil nitrogen stock degradation by microbes leads to the release of various gases, including nitrous oxide (NO), a potent greenhouse gas. Ammonia-oxidizing archaea (AOA) and ammonia-oxidizing bacteria (AOB) participate in the soil nitrogen cycle, producing NO.

Strategies of youth engagement in health promotion: listening sessions, task force participation, surveys and other strategies.

Youth engagement is often purported as a critical dimension of health promotion for young people, but the strategies used to facilitate this engagement are seldom evaluated or studied. This study explored the strategies used to engage youth in a strategic planning process to develop comprehensive health and wellness plans in 28 US school districts. Participating school districts conducted listening sessions, administered anonymous surveys, included youth on a district task force, and employed other strategies to engage youth.

Assessing the Readiness of Rural Public Health Agencies for Facilitating a School-based Intervention.

Background: Partnerships are best positioned for success when the readiness of those engaged is assessed and discussed from the outset. Doing so requires an approach to readiness that is responsive to the particular context of the partnership.

Objectives: This study contributes to the topic of partnership readiness through a readiness assessment used with rural local public health agencies (LPHAs) to partner with a university research team on implementing a Kindergarten to 12th-grade school-based health intervention called Assess, Identify, Make it happen.

A Partnership Among Local Public Health Agencies, Elementary Schools, and a University to Address Childhood Obesity: A Scalable Model of the Assess, Identify, Make It Happen Process.

Background: One pathway to addressing childhood obesity is through implementing evidence-based practices (EBPs) shown to promote nutrition and physical activity in K-12 school settings. Assess, Identify, Make it happen (AIM) is a strategic planning process to engage stakeholders in implementing EBPs in their K-12 schools. Local Public Health Agencies (LPHAs) are a potential partner to facilitate this process to a broader audience of rural school communities.

Precipitation, Not Land Use, Primarily Determines the Composition of Both Plant and Phyllosphere Fungal Communities.

Plant communities and fungi inhabiting their phyllospheres change along precipitation gradients and often respond to changes in land use. Many studies have focused on the changes in foliar fungal communities on specific plant species, however, few have addressed the association between whole plant communities and their phyllosphere fungi. We sampled plant communities and associated phyllosphere fungal communities in native prairie remnants and post-agricultural sites across the steep precipitation gradient in the central plains in Kansas, USA.

You are welcome here: A practical guide to diversity, equity, and inclusion for undergraduates embarking on an ecological research experience.

As we build a more diverse, equitable, and inclusive culture in the ecological research community, we must work to support new ecologists by empowering them with the knowledge, tools, validation, and sense of belonging in ecology to succeed. Undergraduate research experiences (UREs) are critical for a student's professional and interpersonal skill development and key for recruiting and retaining students from diverse groups to ecology. However, few resources exist that speak directly to an undergraduate researcher on the diversity, equity, and inclusion (DEI) dimensions of embarking on a first research experience.

High nitrous oxide fluxes from rice indicate the need to manage water for both long- and short-term climate impacts.

Global rice cultivation is estimated to account for 2.5% of current anthropogenic warming because of emissions of methane (CH), a short-lived greenhouse gas. This estimate assumes a widespread prevalence of continuous flooding of most rice fields and hence does not include emissions of nitrous oxide (NO), a long-lived greenhouse gas.

Antecedent moisture controls on stream nitrate flux in an agricultural watershed.

Evaluating nitrate-N fluxes from agricultural landscapes is inherently complex due to the wide range of intrinsic and dynamic controlling variables. In this study, we investigate the influence of contrasting antecedent moisture conditions on nitrate-N flux magnitude and dynamics in a single agricultural watershed on intra-annual and rainfall-event temporal scales. High temporal resolution discharge and nitrate concentration data were collected to evaluate nitrate-N flux magnitude associated with wet (2009) and dry (2012) conditions.

Pertuzumab and erlotinib in patients with relapsed non-small cell lung cancer: a phase II study using 18F-fluorodeoxyglucose positron emission tomography/computed tomography imaging.

Background: Combination blockade of human epidermal growth factor receptor (HER) family signaling may confer enhanced antitumor activity than single-agent blockade. We performed a single-arm study of pertuzumab, a monoclonal antibody that inhibits HER2 dimerization, and erlotinib in relapsed non-small cell lung cancer (NSCLC).

Methods: Patients received pertuzumab (840-mg loading dose and 420-mg maintenance intravenously every 3 weeks) and erlotinib (150-mg or 100-mg dose orally, daily).

Effects of Trastuzumab Emtansine (T-DM1) on QT Interval and Safety of Pertuzumab Plus T-DM1 in Patients With Previously Treated Human Epidermal Growth Factor Receptor 2-Positive Metastatic Breast Cancer.

Trastuzumab emtansine (T-DM1) is an antibody-drug conjugate in development for human epidermal growth factor receptor 2 (HER2)-positive cancer. Drugs in development are generally tested for their effects on QT interval, prolongation of which is associated with the potentially fatal arrhythmia torsades de pointes. In addition, an association between left ventricular dysfunction and other HER2-directed agents has been documented.

Long-term trends in nitrous oxide emissions, soil nitrogen, and crop yields of till and no-till cropping systems.

No-till cropping can increase soil C stocks and aggregation but patterns of long-term changes in N2O emissions, soil N availability, and crop yields still need to be resolved. We measured soil C accumulation, aggregation, soil water, N2O emissions, soil inorganic N, and crop yields in till and no-till corn-soybean-wheat rotations between 1989 and 2002 in southwestern Michigan and investigated whether tillage effects varied over time or by crop. Mean annual NO3- concentrations in no-till were significantly less than in conventional till in three of six corn years and during one year of wheat production.

Principal atrial fibrillation discharges by the new ACC/AHA/ESC classification.

Background: The American College of Cardiology, American Heart Association, and European Society of Cardiology Board (ACC/AHA/ESC) 2001 guidelines for management of patients with atrial fibrillation (AF) include a new classification system consisting of 4 categories: first-detected episode; recurrent paroxysmal (self-terminating); recurrent persistent (requiring cardioversion); and permanent. The frequency of hospital discharges within these categories has not been reported.

Methods: The new classification system was applied to 135 consecutive hospital discharges with a principal diagnosis of AF.