Complex p53 dynamics regulated by miR-125b in cellular responses to reactive oxidative stress and DNA damage.

In response to distinct cellular stresses, the p53 exhibits distinct dynamics. These p53 dynamics subsequently control cell fate. However, different stresses can generate the same p53 dynamics with different cell fate outcomes, suggesting that the integration of dynamic information from other pathways is important for cell fate regulation.

Relevance between COVID-19 and host genetics of immune response.

The outbreak of coronavirus disease 2019 (COVID-19) was caused by the newly emerged corona virus (2019-nCoV SARS-CoV-2) that resembles the severe acute respiratory syndrome virus (SARS-CoV). SARS-CoV-2, which was first identified in Wuhan (China) has spread globally, resulting in a high mortality worldwide reaching ~4 million deaths to date. As of first week of July 2021, ~181 million cases of COVID-19 have been reported.

Rapid Deployment of a Virtual Nurse Residency Program; Virtually No Idea Where to Start.

The disruption of the COVID-19 pandemic had a significant impact in the transition of the new graduate nurse to independent practice. This article describes the conversion of a nurse residency program from a traditional classroom to a virtual setting and the barriers the team encountered. Curriculum changes and processes are described, including ideas for future implementation.