Publications by authors named "Elsa Charifou"
Twelfth Annual ENBDC Workshop: Methods in Mammary Gland Biology and Breast Cancer.
J Mammary Gland Biol Neoplasia
September 2021
The twelfth annual workshop of the European Network for Breast Development and Cancer focused on methods in mammary gland biology and breast cancer, was scheduled to take place on March 26-28, 2020, in Weggis, Switzerland. Due to the COVID-19 pandemic, the meeting was rescheduled twice and eventually happened as a virtual meeting on April 22 and 23, 2021. The main topics of the meeting were branching and development of the mammary gland, tumor microenvironment, circulating tumor cells, tumor dormancy and breast cancer metastasis.
View Article and Find Full Text PDFThe mammary gland is a highly dynamic tissue that changes throughout reproductive life, including growth during puberty and repetitive cycles of pregnancy and involution. Mammary gland tumors represent the most common cancer diagnosed in women worldwide. Studying the regulatory mechanisms of mammary gland development is essential for understanding how dysregulation can lead to breast cancer initiation and progression.
View Article and Find Full Text PDFArticle Synopsis
- Mammary gland development consists of three stages: puberty, pregnancy and lactation, and involution, involving significant tissue remodeling.
- Three-dimensional (3D) mammary organoid culture is a vital tool for studying mammary gland biology and has advanced our understanding of pubertal development and breast cancer.
- The study presents a new mouse mammary organoid model that effectively mimics lactation and involution processes, providing a valuable platform for researching physiological mechanisms and pregnancy-related breast cancer.