Publications by authors named "Els Van de Perre"

Objectives: IgA vasculitis (IgAV) in adults has been relatively under-investigated. Since outcomes are worse in other forms of vasculitis with increasing age, we investigated the outcomes of IgAV comparing younger adults (18-34), middle aged adults (35-64) and elderly patients (≥64 years) focusing on kidney outcomes.

Methods: We identified patients with renal biopsy confirmed IgAV nephritis and collected data regarding clinical features and progression to end stage kidney disease (ESKD).

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Article Synopsis
  • - Limiting how much oxalate your gut absorbs could help lower oxalate levels in urine for people with conditions like idiopathic and enteric hyperoxaluria.
  • - Phosphate binders, which prevent phosphate absorption in patients with kidney issues, can also interact with oxalate, providing a potential treatment pathway.
  • - This study explores various metallic cations and their ability to bind with phosphate and oxalate, using computational methods to find better ways to deliver these cations into the body.
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Background: The disease course of adult immunoglobulin A (IgA) vasculitis (IgAV; Henoch-Schönlein purpura) has not been well defined.

Methods: In a retrospective survey, we studied 85 adult IgAV patients with extended follow-up (median 43 months) for 67 patients.

Results: Only 33 of 67 (49%) achieved complete remission.

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Encrusted uropathy is a rare subacute to chronic inflammatory disorder caused by infection with urease-producing bacteria, mainly . The disorder is characterized by urothelial deposition of struvite and carbonated apatite, resulting in encrustations and ulceronecrotic inflammation of the urothelium and surrounding tissues. Most commonly, encrusted uropathy is encountered in patients with predisposing conditions.

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Background: Renal pathology in tuberous sclerosis complex (TSC) is characterized by the growth of angiomyolipoma and renal cysts, and in rare cases renal cell carcinoma. Other consequences of renal involvement in TSC, including hypertension, proteinuria, and hyperfiltration, are not well studied. We aimed to analyze the early manifestations of the renal TSC phenotype in a young TSC cohort and to explore common, modifiable risk factors.

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