Publications by authors named "Eloise Leclerc"
Article Synopsis
- - The study evaluated the effectiveness of a nationwide anal cancer screening program for high-risk HIV patients in France, focusing on adherence to the program and cancer diagnosis rates.
- - Out of 700 patients, those with higher grades of anal intra-epithelial neoplasia (AIN) faced significantly increased risks of developing anal cancer, but strict adherence to screening (only 4.6% of participants) did not show a decrease in cancer risk.
- - Despite not diagnosing any anal cancer among adherent patients, the screening led to more frequent diagnoses of anal warts, indicating a need for further investigation into the program's actual impact on cancer risk reduction.
Article Synopsis
- Monkeypox is a zoonotic disease originally from Africa that recently saw a global outbreak starting in April 2022, with limited understanding of its transmission.
- This observational study analyzed anal symptoms in 65 men diagnosed with monkeypox at a proctology unit in Paris during mid-2022, focusing on the association with sexually transmitted infections.
- Key findings revealed that a high percentage of cases involved sexual transmission, primarily among men who have sex with men, with common symptoms being painful anal and perianal ulcerations, and most patients experienced complete symptom resolution within 12 days.
Background: Data comparing tofacitinib and vedolizumab in ulcerative colitis (UC) are lacking.
Aims: To compare the effectiveness of tofacitinib and vedolizumab in patients with UC who had prior exposure to anti-TNF therapy METHODS: In this multicentre study, we included consecutive patients with UC ≥18 years old with partial Mayo score >2 and prior anti-TNF exposure, who started tofacitinib or vedolizumab between January 2019 and June 2021. Comparisons were performed using propensity score analyses (inverse probability of treatment weighting).