Publications by authors named "Eloi Prud'homme"
Article Synopsis
- The study aimed to evaluate whether placing COVID-19 patients with acute respiratory failure in an awake prone position (aPP) could improve lung ventilation uniformity as measured by electrical impedance tomography (EIT).
- The study involved 20 patients who were tested in both the supine position and aPP, measuring their oxygenation levels and EIT readings after each interval.
- Results showed that while oxygenation improved in aPP, the global inhomogeneity index of ventilation did not significantly change in either position, indicating that aPP does not reduce lung ventilation inhomogeneity in these patients.
Unlabelled: To determine the effect of the awake prone position (APP) on gas exchange and the work of breathing in spontaneously breathing patients with COVID-19-associated acute hypoxemic respiratory failure (AHRF) supported by high-flow nasal oxygen.
Design: Prospective randomized physiologic crossover multicenter trial.
Settings: Four ICUs in Marseille, France.
Prone positioning reduces mortality in the management of intubated patients with moderate-to-severe acute respiratory distress syndrome. It allows improvement in oxygenation by improving ventilation/perfusion ratio mismatching.Because of its positive physiological effects, prone positioning has also been tested in non-intubated, spontaneously breathing patients, or "awake" prone positioning.
View Article and Find Full Text PDFNon-intubated patients with acute respiratory failure due to COVID-19 could benefit from awake proning. Awake proning is an attractive intervention in settings with limited resources, as it comes with no additional costs. However, awake proning remains poorly used probably because of unfamiliarity and uncertainties regarding potential benefits and practical application.
View Article and Find Full Text PDFIt is unknown if solid organ transplant recipients are at higher risk for severe COVID-19. The management of a lung transplantation (LTx) program and the therapeutic strategies to adapt the immunosuppressive regimen and antiviral measures is a major issue in the COVID-19 era, but little is known about worldwide practice. We sent out to 180 LTx centers worldwide in June 2020 a survey with 63 questions, both regarding the management of a LTx program in the COVID-19 era and the therapeutic strategies to treat COVID-19 LTx recipients.
View Article and Find Full Text PDFThis case series describes the proportion of awake, nonintubated inpatients with COVID-19 and hypoxemic respiratory failure requiring oxygen supplementation whose Pao increased ≥20% with prone positioning, and their respiratory status after resuming supine positioning.
View Article and Find Full Text PDFBackground: Infection is the most common cause of mortality within the first year after lung transplantation (LTx). The management of perioperative antibiotic therapy is a major issue, but little is known about worldwide practices.
Methods: We sent by email a survey dealing with 5 daily clinical vignettes concerning perioperative antibiotic therapy to 180 LTx centers around the world.