Publications by authors named "Elodie Teclaire Ngo-Malabo"
Article Synopsis
- In Cameroon, the study focuses on identifying viral causes of meningoencephalitis (ME), particularly herpesviruses and enteroviruses, as current diagnoses mainly detect bacterial and fungal infections.
- Conducted from February to May 2018, the research included 81 adult patients in Yaounde, revealing that 18.51% were positive for herpesviruses, primarily Epstein-Barr virus, especially among HIV-positive individuals.
- A high mortality rate of 60.5% was observed, with risk factors like HIV-positive status and altered consciousness linked to increased death rates, highlighting the need for improved awareness and management of CNS infections in Cameroon.
HIV-1 group N (HIV-1/N) remains rare and mainly restricted to Cameroon. In this study, we report a new HIV-1/N infected case identified during routine HIV screening activities in Yaounde. The genetic characterization of the near full-length genome of this virus strain revealed that it is genetically distinct to all HIV-1/N described to date.
View Article and Find Full Text PDFBackground: HIV infection in Cameroon is characterized by a great viral diversity with all HIV-1 groups (M, N, O, and P) and HIV-2 in circulation. HIV group determination is very important if tailored viral load analysis and treatments are to be applied. In our laboratory, HIV viral load is carried out using two platforms; Biocentric and Abbott depending on the HIV group identified.
View Article and Find Full Text PDFBackground: First line antiretroviral therapy in a resource-limited setting consists of nucleotide and non-nucleotide reverse transcriptase inhibitors. Protease inhibitors are the hub of second line therapy. The decision to change antiretroviral therapy for a patient is frequently presumptive because of the lack of genotypic resistance tests in routine follow-up.
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