Environmental heat stress offsets adaptation associated with carbohydrate periodization in trained male triathletes.

Purpose: Carbohydrate (CHO) intake periodization via the sleep low train low (SL-TL) diet-exercise model increases fat oxidation during exercise and may enhance endurance-training adaptation and performance. Conversely, training under environmental heat stress increases CHO oxidation, but the potential of combined SL-TL and heat stress to enhance metabolic and performance outcomes is unknown.

Methods: Twenty-three endurance-trained males were randomly assigned to either control (n = 7, CON), SL-TL (n = 8, SL ) or SL-TL + heat stress (n = 8, SL ) groups and prescribed identical 2-week cycling training interventions.

Acute heat stress amplifies exercise-induced metabolomic perturbations and reveals variation in circulating amino acids in endurance-trained males.

New Findings: What is the central question of this study? Whole-body substrate utilisation is altered during exercise in hot environments, characterised by increased glycolytic metabolism: does heat stress alter the serum metabolome in response to high intensity exercise? What are the main finding and its importance? Alongside increases in glycolytic metabolite abundance, circulating amino acid concentrations are reduced following exercise under heat stress. Prior research has overlooked the impact of heat stress on protein metabolism during exercise, raising important practical implications for protein intake recommendations in the heat.

Abstract: Using untargeted metabolomics, we aimed to characterise the systemic impact of environmental heat stress during exercise.

[An unexpected delivery in Mayotte].

The particular social-cultural context of Mayotte is resulting in an increase in the number of unexpected home births. When a secondary emergency response vehicle is dispatched, A & E nurses are involved in providing prehospital care, sometimes in difficult conditions, as one nurse testifies in this account.