Antidepressant agents in short bowel syndrome.

Purpose: This study aimed to determine whether short small intestine modifies antidepressant concentrations.

Methods: The Css values and concentration-dose ratios (CDRs) of citalopram or escitalopram, administered orally or intravenously, were determined in patients with short bowel syndrome.

Findings: Eight patients (6 males and 2 females) were included in the study.

[Use of oral drugs and short bowel syndrome: an analysis of practices].

Objective: To describe drug prescription patterns in patients with short bowel syndrome (SBS).

Methods: The drug prescriptions of patients suffering from SBS type 1 to 3 were compared.

Results: Seventy-nine percent of the drugs were prescribed by oral route, and this proportion was significantly higher in patients with type 3 compared to tose with type 1.

Absorption and efficacy of acetylsalicylic acid in patients with short bowel syndrome.

Background: The patients with a short bowel (SB) frequently require antiplatelet therapy. Resection of the bowel is likely to modify the absorption and first-pass effect of drugs. No data on the absorption and efficacy of the cardiovascular dose of aspirin (75-160 mg) in these patients have been published.