Publications by authors named "Elodie Bouvier"
Long-term evolution data of olfactory disorders (OD) in COVID-19 are limited. ANOSVID is a retrospective study in Nord Franche-Comté Hospital (France) that included COVID-19 patients from the first wave. The aim was to describe OD evolution, especially in patients with persistent OD (p-OD group) in comparison with patients with resolved OD (r-OD group).
View Article and Find Full Text PDFOlfactory disorders (OD) pathogenesis, underlying conditions, and prognostic in coronavirus disease 2019 (COVID-19) remain partially described. ANOSVID is a retrospective study in Nord Franche-Comté Hospital (France) that included COVID-19 patients from March 1 2020 to May 31 2020. The aim was to compare COVID-19 patients with OD (OD group) and patients without OD (no-OD group).
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- The study investigates the prognostic value of chest CT characteristics in COVID-19 patients, aiming to better understand factors influencing mortality.
- A retrospective analysis of 515 patients was conducted, revealing that advanced age and significant pulmonary involvement on CT scans were linked to higher in-hospital mortality rates within 30 days.
- Key findings highlight that CT indicators like over 50% lung involvement, pleural effusions, and nodular consolidations are critical for assessing severe cases of COVID-19 and guiding treatment decisions.
Article Synopsis
- Accumulation of stressful experiences can increase the risk of developing epilepsy and related issues, but it's uncertain if this vulnerability can be anticipated or undone.
- A study on rats showed that social defeat didn't cause depression on its own, but it did lower the threshold for seizures and led to cognitive and mood problems after epilepsy developed in 50% of cases.
- Low levels of brain-derived neurotrophic factor (BDNF) before seizures helped identify vulnerable individuals, and administering a BDNF analog before seizures could prevent these additional problems from occurring.
Article Synopsis
- * After a stress event, while normal hormone levels returned in all animals, only 58% showed full recovery in other biological measures, indicating a subgroup (nonvulnerable) that remained unaffected.
- * The remaining 42% (vulnerable group) exhibited persistent changes linked to depression, and a specific treatment helped mitigate these depressive symptoms, highlighting BDNF levels as a potential biomarker for depression risk.