Publications by authors named "Elodie Akary"
P4B (2-phenyl-1-[4-(6-(piperidin-1-yl) pyridazin-3-yl) piperazin-1-yl] butan-1-one) is a novel cellulose biosynthesis inhibitor (CBI) discovered in a screen for molecules to identify inhibitors of Arabidopsis (Arabidopsis thaliana) seedling growth. Growth and cellulose synthesis inhibition by P4B were greatly reduced in a novel mutant for the cellulose synthase catalytic subunit gene CESA3 (cesa3pbr1). Cross-tolerance to P4B was also observed for isoxaben-resistant (ixr) cesa3 mutants ixr1-1 and ixr1-2.
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- The hydrostatic skeleton of plants is formed by pressurized cells with strong walls, which rely on RAPID ALKALINIZATION FACTOR (RALF) peptides for assembly and expansion.
- The RALF22 peptide plays a key role in root hair cell expansion by compacting pectin polymers and forming a complex with other proteins, triggering adaptive cellular responses.
- This study reveals that RALF peptides serve both structural and signaling functions in plant cell wall organization, suggesting a broader application in various plant cell types.
The conjugation of sterols with a Glc moiety is catalyzed by sterol glucosyltransferases (SGTs). A portion of the resulting steryl glucosides (SG) are then esterified with a long-chain fatty acid to form acyl-SG (ASG). SG and ASG are prevalent components of plant cellular membranes and influence their organization and functional properties.
View Article and Find Full Text PDFEnterococcus faecalis is a nosocomial opportunistic pathogen, but is also found in fermented food products where it plays a fundamental role in the fermentation process. Previously, we have described the non-starter E. faecalis cheese isolate QA29b as harboring virulence genes and proven to be virulent in Galleria mellonella virulence model.
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- - A study analyzed 126 French cheeses and found that 44% of pasteurized and 92% of raw-milk cheeses contained enterococci, with E. faecalis being the most common resistant species (81%).
- - High levels of antibiotic resistance were observed, particularly against tetracycline and minocycline, with many isolates exhibiting multiple resistance patterns.
- - Despite the presence of antibiotic-resistant enterococci, the low occurrence of highly resistant strains suggests that French cheeses are not a significant source of multi-drug resistant enterococci for hospitals.