Publications by authors named "Elodia-Nataly Diaz-de-la-Cruz"
Article Synopsis
- Methotrexate (MTX) is commonly used for treating psoriasis but can cause kidney damage, which antioxidants like vitamin C (vitC) might mitigate.
- A study using a mouse model of psoriasis explored how vitC impacts kidney toxicity from high doses of MTX, finding that while vitC can reduce kidney damage, it may worsen skin lesions and kidney injury when combined with IMQ (a psoriasis-inducing agent).
- The findings indicate that vitC could be beneficial for renal protection in psoriasis but should not be used alongside MTX in patients with existing kidney issues.
The Influence of the Severity of Early Chronic Kidney Disease on Oxidative Stress in Patients with and without Type 2 Diabetes Mellitus.
Int J Mol Sci
September 2022
Early Chronic Kidney Disease (CKD) is a condition that tends to progress to End-Stage Kidney Disease (ESKD). Early diagnosis of kidney disease in the early stages can reduce complications. Alterations in renal function represent a complication of diabetes mellitus (DM).
View Article and Find Full Text PDFThe clinical and biochemical improvement observed in kidney transplant (RT) recipients is remarkable. The correct functioning of the allograft depends on various factors such as the donor's age, the alloimmune response, the ischemia-reperfusion injury, arterial hypertension, and the interstitial fibrosis of the allograft, among others. Antihypertensive drugs are necessary for arterial hypertension patients to avoid or reduce the probability of affecting graft function in RT recipients.
View Article and Find Full Text PDFThe Influence of Sevelamer Hydrochloride and Calcium Carbonate on Markers of Inflammation and Oxidative Stress in Hemodialysis at Six Months of Follow-Up.
Front Med (Lausanne)
November 2021
Patients with end-stage renal disease (ESRD) present alterations in mineral and bone metabolism. Hyperphosphatemia in ESRD is considered an independent risk factor for cardiovascular disease (CVD), increasing morbidity, and mortality. Sevelamer hydrochloride is a calcium-free, non-absorbable phosphate-chelating polymer.
View Article and Find Full Text PDFDonors have a higher risk of developing chronic kidney disease than the general population. Some mechanisms mediated by pro-inflammatory cytokines and oxidative stress may be involved as risk factors. The objective of the study was to evaluate the behavior of pro-inflammatory cytokines and oxidative stress markers in living renal donors with a 6-month follow-up.
View Article and Find Full Text PDFThe Effect of Visceral Abdominal Fat Volume on Oxidative Stress and Proinflammatory Cytokines in Subjects with Normal Weight, Overweight and Obesity.
Diabetes Metab Syndr Obes
April 2020
Purpose: The increase of visceral abdominal fat (VAF) and oxidative stress (OS) are independent predictors for cardiovascular risk. This study aimed to determine the association of VAF with proinflammatory cytokines, oxidants, antioxidants, and oxidative damage to DNA in subjects with normal weight, overweight, and obesity.
Patients And Methods: A cross-sectional study that included 21 men and 71 women who attended for a medical check-up was conducted.