Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub
July 2006
Article Synopsis
The study evaluates the cardioprotective effects of osajin and pomiferin, two compounds isolated from the fruit of Maclura pomifera, using rat hearts as a model for testing antioxidant therapy against ischemia-reperfusion injury.
The research involved four groups of Wistar rats, where two groups received the isoflavones, while the other two served as a placebo and control group, with various biochemical and functional heart parameters measured after treatment.
Results indicated that both osajin and pomiferin improved heart function and decreased oxidative stress, suggesting their potential as protective agents against heart damage caused by ischemia-reperfusion events.