A rapid colorimetric paper-based sensor strip for point-of-care monitoring of the blood plasma coagulation.

Coagulation disorders can lead to dangerous bleeding or clot formation. Since centralized laboratories cannot provide rapid results for timely treatment intervention in patients with coagulation disorders, the existence of coagulation sensors for the general public is necessary. The purpose of the present research is to design and fabricate a novel, portable, low-cost, paper-based colorimetric sensor for measuring blood prothrombin time.

Microfluidic paper and thread-based separations: Chromatography and electrophoresis.

Paper and thread are widely used as the substrates for fabricating low-cost, disposable, and portable microfluidic analytical devices used in clinical, environmental, and food safety monitoring. Concerning separation methods including chromatography and electrophoresis, these substrates provide unique platforms for developing portable devices. This review focuses on summarizing recent research on the miniaturization of the separation techniques using paper and thread.

An All-in-One Solid State Thin-Layer Potentiometric Sensor and Biosensor Based on Three-Dimensional Origami Paper Microfluidics.

An origami three-dimensional design of a paper-based potentiometric sensor is described. In its simplest form, this electrochemical paper-based analytical device (ePAD) is made from three small parts of the paper. Paper layers are folded on each other for the integration of a solid contact ion selective electrode (here a carbon-paste composite electrode) and a solid-state pseudo-reference electrode (here writing pencil 6B on the paper), which are in contact with a hydrophilic channel fabricated on the middle part (third part) of the paper.

Colorimetric and visual determination of hydrogen peroxide and glucose by applying paper-based closed bipolar electrochemistry.

A disposable paper-based bipolar electrochemical biosensor is reported for determination of glucose. The closed bipolar electrochemical cell is fabricated on a small part of paper using a laser printing-based process for paper hydrophobization. The bipolar and driving electrodes are provided by pressing the writing pencil HB on the paper.